Find coaches from Santa Ana, US to San Francisco, US

Next bus departures

Next departures from Santa Ana to San Francisco on 14 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Anaheim Regional Transportation Intermodal Center
San Francisco Bus StationCheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Anaheim Regional Transportation Intermodal Center
409 Townsend St, SFNo tags
Greyhound Lines, Inc.Bus
Santa Ana Bus Station
San Francisco Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Santa Ana Bus Station
409 Townsend St, SFNo tags

Last refresh of the prices: Yesterday at 2:47 PM PST.

Get from Santa Ana to San Francisco

This route is served by bus only

The journey takes about 11 hours 10 minutes, and with fares starting at just R 870, it presents an excellent value for a comfortable ride.

7bus per day
11h 10mAverage duration
607 kmDistance
15kgCO₂ emissions

Frequently asked questions about travelling from Santa Ana, US to San Francisco, US by bus

  1. How much does a bus ticket from Santa Ana to San Francisco cost?

    The bus ticket price from Santa Ana to San Francisco starts at R 870. The best way to find cheap bus tickets from Santa Ana to San Francisco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Santa Ana to San Francisco?

    The average travel time between Santa Ana and San Francisco is around 11h 10m, although the fastest bus will take about 9h 35m. This is the time it takes to travel the 609 km that separates the two cities.

  3. How many daily bus connections are there between Santa Ana and San Francisco?

    The number of buses from Santa Ana to San Francisco can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Ana to San Francisco by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Santa Ana to San Francisco?

    When taking the bus from Santa Ana to San Francisco, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Santa Ana to San Francisco?

    Buses travelling between Santa Ana and San Francisco leave from Santa Ana Greyhound Bus Station or 602 S Main St and arrive at Hyde/Beach (Fisherman's Wharf), Powell Station, Union Square Hilton.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/11
R 981
13/11
R 2 041
Today
R 2 768
15/11
No data
16/11
R 2 103
17/11
R 824
18/11
No data
19/11
R 1 384
busbud logoThe cheapest trip from Santa Ana, US to San Francisco, US was searched and found on 17 Nov 2025 with a price of R 824

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to San Francisco, US as early as possible.

You can expect to pay from R 824 to R 2 768 for a bus ticket from Santa Ana, US to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 824, which is on 2025-11-17.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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