Find coaches from San Ysidro, CA to Santa Ana, US

Next bus departures

Next departures from San Ysidro to Santa Ana on 15 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
San Ysidro Bus terminal
Santa Ana Bus StationCheapest
Los LimousinesBus
San Ysidro Greyhound Bus Station
Santa Ana E Santa Ana BlvdFastest
FlixBusBus
San Ysidro Bus terminal
Anaheim Regional Transportation Intermodal CenterNo tags
Greyhound Lines, Inc.Bus
San Ysidro Bus terminal
Anaheim Regional Transportation Intermodal CenterNo tags
Los LimousinesBus
San Ysidro Greyhound Bus Station
Santa Ana E Santa Ana BlvdNo tags

Last refresh of the prices: Today at 8:26 AM PST.

Get from San Ysidro to Santa Ana

This route is served by bus only

The journey takes about 2 hours 45 minutes, and with fares starting at just R 415, it presents an excellent value for a comfortable ride.

19bus per day
2h 45mAverage duration
155 kmDistance
4kgCO₂ emissions

Frequently asked questions about travelling from San Ysidro, CA to Santa Ana, US by bus

  1. How much does a bus ticket from San Ysidro to Santa Ana cost?

    The bus ticket price from San Ysidro to Santa Ana starts at R 415. The best way to find cheap bus tickets from San Ysidro to Santa Ana is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Ysidro to Santa Ana?

    The average travel time between San Ysidro and Santa Ana is around 2h 45m, although the fastest bus will take about 2h. This is the time it takes to travel the 154 km that separates the two cities.

  3. How many daily bus connections are there between San Ysidro and Santa Ana?

    The number of buses from San Ysidro to Santa Ana can differ depending on the day of the week. On average, there are 19 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Ysidro to Santa Ana by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Ysidro to Santa Ana?

    When taking the bus from San Ysidro to Santa Ana, you can travel comfortably and safely with Los Limousines, FlixBus, Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/11
No data
13/11
R 316
Today
R 543
15/11
R 377
16/11
R 351
17/11
R 307
18/11
R 289
19/11
R 298
busbud logoThe cheapest trip from San Ysidro, CA to Santa Ana, US was searched and found on 18 Nov 2025 with a price of R 289

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Santa Ana, US as early as possible.

You can expect to pay from R 289 to R 964 for a bus ticket from San Ysidro, CA to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 289, which is on 2025-11-18.

Usually FlixBus, Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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