Find coaches from San Francisco, US to Chicago

Next departures

Next departures from San Francisco to Chicago on 14 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
San Francisco Bus Station
Chicago 95Th & Dan RyanCheapestFastest
Amtrak
Mission St & Fremont St
Chicago (Union Station), ILNo tags
Greyhound Lines, Inc. + FlixBus
San Francisco Bus Station
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
San Francisco Bus Station
537-517 W. Jackson BlvdNo tags
Amtrak
Mission St & Fremont St
Chicago (Union Station), ILNo tags

Last refresh of the prices: Last Monday at 8:52 PM PST.

Get from San Francisco to Chicago

This route is served by bus only

The journey takes about 2 days, 15 hours 15 minutes, and with fares starting at just R 2 437, it presents an excellent value for a comfortable ride.

15bus per day
2d 15hAverage duration
2982 kmDistance
75kgCO₂ emissions

Frequently asked questions about travelling from San Francisco, US to Chicago by bus

  1. How much does a bus ticket from San Francisco to Chicago cost?

    The bus ticket price from San Francisco to Chicago starts at R 2 437. The best way to find cheap bus tickets from San Francisco to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from San Francisco to Chicago?

    The average travel time between San Francisco and Chicago is around 2d 15h, although the fastest bus will take about 2d 1h. This is the time it takes to travel the 2987 km that separates the two cities.

  3. How many daily bus connections are there between San Francisco and Chicago?

    The number of buses from San Francisco to Chicago can differ depending on the day of the week. On average, there are 15 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Francisco to Chicago by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from San Francisco to Chicago?

    When taking the bus from San Francisco to Chicago, you can travel comfortably and safely with Amtrak, Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from San Francisco to Chicago?

    Buses travelling between San Francisco and Chicago leave from Hyde/Beach (Fisherman's Wharf) or Powell Station and arrive at Downtown Greyhound Station, Chicago O'Hare International Airport, Polk St & Canal St.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/11
R 4 552
13/11
R 3 304
Today
R 5 360
15/11
No data
16/11
No data
17/11
No data
18/11
No data
19/11
No data
busbud logoThe cheapest trip from San Francisco, US to Chicago was searched and found on 13 Nov 2025 with a price of R 3 304

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Chicago as early as possible.

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