How much does a bus ticket from San Antonio to St. Louis cost?

The bus ticket price from San Antonio to St. Louis starts at R 1 490. The best way to find cheap bus tickets from San Antonio to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from San Antonio to St. Louis?

The average travel time between San Antonio and St. Louis is around 1d 1h, although the fastest bus will take about 20h 45m. This is the time it takes to travel the 1278 km that separates the two cities.

How many daily bus connections are there between San Antonio and St. Louis?

The number of buses from San Antonio to St. Louis can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Antonio to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from San Antonio to St. Louis?

When taking the bus from San Antonio to St. Louis, you can travel comfortably and safely with Greyhound, Valley Transit.

What are the departure and arrival stations when taking the bus from San Antonio to St. Louis?

Buses travelling between San Antonio and St. Louis leave from San Antonio Bus Station or Tornado I-35 and arrive at Gateway Station.

Bus San Antonio to St. Louis from R 1 618 | Refundable Tickets

Next bus departures

Next departures from San Antonio to St. Louis on 12 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Valley Transit + Greyhound Lines, Inc.	Bus	21:15	San Antonio Bus Station	1d 1h	22:50	Gateway Station	Cheapest
	Bus	12:40	San Antonio Bus Station	1d	12:55	Gateway Station	Fastest

Next departures from San Antonio to St. Louis on 13 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	01:30	San Antonio Bus Station	21h 20m	22:50	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	07:30	San Antonio Bus Station	23h 40m	07:10	Gateway Station	No tags
	Bus	12:40	San Antonio Bus Station	1d	12:55	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	21:15	San Antonio Bus Station	1d 1h	22:50	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	07:45	Pearl District	23h 25m	07:10	Gateway Station	No tags

Next departures from San Antonio to St. Louis on 14 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	01:30	San Antonio Bus Station	21h 20m	22:50	Gateway Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	07:30	San Antonio Bus Station	23h 40m	07:10	Gateway Station	No tags
	Bus	12:40	San Antonio Bus Station	1d	12:55	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	21:15	San Antonio Bus Station	1d 1h	22:50	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	07:45	Pearl District	23h 25m	07:10	Gateway Station	No tags

Next departures from San Antonio to St. Louis on 15 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	12:40	San Antonio Bus Station	1d	12:55	Gateway Station	Cheapest
Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	01:30	San Antonio Bus Station	21h 20m	22:50	Gateway Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	07:30	San Antonio Bus Station	23h 40m	07:10	Gateway Station	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	21:15	San Antonio Bus Station	1d 1h	22:50	Gateway Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	07:45	Pearl District	23h 25m	07:10	Gateway Station	No tags

Last refresh of the prices: Yesterday at 12:20 PM CST.

Compare 2 ways to travel from San Antonio to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 1 day, 42 minutes and with fares starting at just R 1 970, it presents an excellent value for a comfortable ride.

1train per day

1d Average duration

1276 kmDistance

116kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 1 490 - R 6 107	Average duration1d 1h	CO₂ emissions 32kg CO₂e
Train	Average priceR 1 970 - R 5 848	Average duration1d	CO₂ emissions 116kg CO₂e

Compare bus companies

Greyhound

3.5/587 369 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Valley Transit

3/533 reviews

Staff3.8

Timeliness3.4

Cleanliness2.9

WiFi2.3

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in San Antonio and St. Louis?

Stops in San Antonio

A - San Antonio Bus Station

B - Tornado I-35

C - San Antonio, TX

D - 4407 S PanAm Expy #101

Stops in St. Louis

A - Gateway Station

Frequently asked questions about travelling from San Antonio, US to St. Louis by bus

How much does a bus ticket from San Antonio to St. Louis cost?
The bus ticket price from San Antonio to St. Louis starts at R 1 490. The best way to find cheap bus tickets from San Antonio to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from San Antonio to St. Louis?
The average travel time between San Antonio and St. Louis is around 1d 1h, although the fastest bus will take about 20h 45m. This is the time it takes to travel the 1278 km that separates the two cities.
How many daily bus connections are there between San Antonio and St. Louis?
The number of buses from San Antonio to St. Louis can differ depending on the day of the week. On average, there are 5 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Antonio to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from San Antonio to St. Louis?
When taking the bus from San Antonio to St. Louis, you can travel comfortably and safely with Greyhound, Valley Transit.
What are the departure and arrival stations when taking the bus from San Antonio to St. Louis?
Buses travelling between San Antonio and St. Louis leave from San Antonio Bus Station or Tornado I-35 and arrive at Gateway Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/11

R 3 096

11/11

R 3 448

Today

R 3 905

13/11

R 3 870

14/11

R 3 782

15/11

R 2 586

16/11

R 2 744

17/11

R 1 618

The cheapest trip from San Antonio, US to St. Louis was searched and found on 17 Nov 2025 with a price of R 1 618

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to St. Louis as early as possible.

You can expect to pay from R 1 618 to R 3 905 for a bus ticket from San Antonio, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 618, which is on 2025-11-17.