Train tickets from Prague to Brussels

Next train departures

Next departures from Prague to Brussels on 16 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
EuroCity Train + InterCity + Regional-Express
Train
Hlavní nádraží
Brussels Central Train StationCheapestFastest
European SleeperTrain
    Hlavní nádraží
    Brussels South/Midi Train StationNo tags
    EuroCity Train + InterCity + Regional-Express
    Train
    Hlavní nádraží
    Brussels Central Train StationNo tags
    EuroCity Train + InterCity + Regional-Express
    Train
    Hlavní nádraží
    Brussels Central Train StationNo tags
    EuroCity Train + InterCity + Regional-Express
    Train
    Hlavní nádraží
    Brussels Central Train StationNo tags

    Last refresh of the prices: Last Thursday at 08:31 CET.

    Compare 2 ways to travel from Prague to Brussels

    We recommend taking the bus

    Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 30 minutes and with fares starting at just £35, it presents an excellent value for a comfortable ride.

    17bus per day
    18h 30mAverage duration
    439 milesDistance
    18kgCO₂ emissions
    Average price£35 - £190Average duration18h 30m
    18kg CO₂e
    Average price£48 - £204Average duration15h 10m
    17kg CO₂e

    Frequently asked questions about travelling from Prague to Brussels by train

    1. How much does a cheap train ticket from Prague to Brussels cost?

      The average train ticket price from Prague to Brussels is £104. The best way to find cheap train tickets from Prague to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the train trip from Prague to Brussels?

      A train trip between Prague and Brussels is around 15h 10m, although the fastest train will take about 11h 1m. This is the time it takes to travel the 446 miles that separates the two cities.

    3. How many daily train are there between Prague and Brussels?

      The number of trains from Prague to Brussels can differ depending on the day of the week. On average, there are 4. Some trains are direct while others include transferring trains. Simplify your train trip from Prague to Brussels by comparing and selecting the train that fits your travel style and budget on Busbud.

    4. What are the departure and arrival stations for a train from Prague to Brussels?

      Trains travelling between Prague and Brussels leave from Hlavní nádraží or Florenc and arrive at Brux-Nord, Brussels South (Gare du Midi), Bruxelles / Brussels Central.

    Find cheapest prices for trains

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    13/11
    £195
    14/11
    No data
    Today
    No data
    16/11
    £176
    17/11
    No data
    18/11
    £121
    19/11
    No data
    20/11
    £140
    busbud logoThe cheapest trip from Prague to Brussels was searched and found on 18 Nov 2025 with a price of £121

    To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Brussels as early as possible.

    You can expect to pay from £121 to £883 for a train ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £121, which is on 2025-11-18.

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