Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Hlavní nádraží | Brussels South/Midi Train Station | Cheapest | |||||
| Hlavní nádraží | Brussels South/Midi Train Station | Fastest | |||||
| Hlavní nádraží | Brussels South/Midi Train Station | No tags | |||||
| Hlavní nádraží | Brussels South/Midi Train Station | No tags | |||||
| Hlavní nádraží | Brussels South/Midi Train Station | No tags |
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Compare 2 ways to travel from Prague to Brussels
Busbud recommends taking the train from Prague to BrusselsAmong the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 11 hours 14 minutes and with fares starting at just US$77, it presents an excellent value for a comfortable ride.
Train Prague to Brussels: Trip Overview
Please note, this information is subject to change.
Prague to Brussels Train
With Busbud, comparing and booking tickets for a train from Prague to Brussels is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Prague to Brussels from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Brussels from Prague, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Prague and Brussels?
Frequently asked questions on the trip Prague - Brussels
How much does a cheap train ticket from Prague to Brussels cost?
The average train ticket price from Prague to Brussels is US$131. The best way to find cheap train tickets from Prague to Brussels is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Prague to Brussels?
A train trip between Prague and Brussels is around 11h 14m, although the fastest train will take about 11h 1m. This is the time it takes to travel the 446 miles that separates the two cities.
How many daily train are there between Prague and Brussels?
The number of trains from Prague to Brussels can differ depending on the day of the week. On average, there are 6. Some trains are direct while others include transferring trains. Simplify your train trip from Prague to Brussels by comparing and selecting the train that fits your travel style and budget on Busbud.
What are the departure and arrival stations for a train from Prague to Brussels?
Trains travelling between Prague and Brussels leave from Hlavní nádraží or Florenc and arrive at Brux-Nord, Brussels South (Gare du Midi), Bruxelles / Brussels Central.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Brussels was searched and found on 30 Sept 2025 with a price of US$120To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Brussels as early as possible.
You can expect to pay from US$120 to US$1,140 for a train ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$120, which is on 2025-09-30.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Prague to Brussels is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Brussels you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Prague and Brussels, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Prague to Brussels and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Japanese trains are always on time. It is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologise to each passenger.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.
Top Travelled Train Routes
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