Find coaches from Palermo to Milano

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Today10 Aug
from US$122
Tomorrow11 Aug
from US$83
Tue12 Aug
Wed13 Aug
from US$120
Thu14 Aug
from US$91
Fri15 Aug
Sat16 Aug
Sun17 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 11 August at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: 12 August at
    Destination city: Milano
    Destination location: Lampugnano bus station
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 11 August at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: 12 August at
    Destination city: Milano
    Destination location: Milan San Donato Bus Station
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: 11 August at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: 12 August at
    Destination city: Milano
    Destination location: Lampugnano
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: 11 August at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: 12 August at
    Destination city: Milano
    Destination location: Milan (Malpensa Aeroporto Terminal 1)
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 11 August at
    Departure city: Palermo
    Departure location: Terminal Bus Palermo
    Arrival time: 12 August at
    Destination city: Milano
    Destination location: Milan San Donato Bus Station
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:

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Compare 2 ways to travel from Palermo to Milano

Bus
Average priceUS$61 - US$240Average duration1d
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$116 - US$116Average duration16h
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Palermo to Milano

Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 16 hours and with fares starting at just US$116, it presents an excellent value for a comfortable ride.

1carpool per day
16hAverage duration
US$116Cheapest ticket
37kgCO₂ emissions

Bus Palermo to Milano: Trip Overview

Average ticket priceUS$124
Average bus trip duration1d
Number of daily buses13
Earliest bus departure09:10
Distance554 miles
Latest bus departure19:45

Palermo to Milano Bus

With Busbud, comparing and booking tickets for a bus from Palermo to Milano is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Palermo to Milano.

Discover how much the bus trip from Palermo to Milano will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Palermo - Milano

  1. What's the distance between Palermo and Milano by coach?

    The journey from Palermo to Milano by coach covers an approximate distance of 551 miles (888 km).

  2. What is the best way to go from Palermo to Milano without flying?

    To travel from Palermo to Milano without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/08
US$70
09/08
US$61
Today
US$110
11/08
US$79
12/08
US$106
13/08
US$116
14/08
US$87
15/08
US$107
busbud logoThe cheapest trip from Palermo to Milano was searched and found on 9 Aug 2025 with a price of US$61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Milano as early as possible.

You can expect to pay from US$61 to US$236 for a bus ticket from Palermo to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at US$79, which is on 2025-08-11.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Palermo to Milano.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Palermo to Milano.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Palermo to Milano will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Palermo to Milano, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Palermo by bus?

Bus from Palermo to Milano

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